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In our February/March issue:
COLUMNS
LC TROUBLESHOOTING
Troubleshooting Trends
How to avoid problems caused by contaminated solvents and sample solvents. Read more >>
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Application Note
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PHARMACEUTICAL PERSPECTIVES
Modern Methods to Identify Counterfeit Medicines and Health Products
This review intends to give a general overview of the liquid chromatographic (LC) and gas chromatographic (GC) methods, utilized by regulatory authorities, for the detection and characterization of suspected illegal medicines and health products, including lifesaving drugs, lifestyle drugs, and biotechnology drugs.
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COLUMN WATCH
Characterizing Complex Biotherapeutics
This month's "Column Watch" describes advances in "bottom-up" analysis of monoclonal antibodies while highlighting the role and importance column chemistry still plays in developing highly selective HPLC methods for peptides.
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THE ESSENTIALS
Hydrophobic Interaction Chromatography of Proteins
A discussion of hydrophobic interaction chromatography (HIC) theory and its application to the analysis of proteins and biomolecules is presented.
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PEER-REVIEWED ARTICLE
Advances in the Analysis of Emerging Drugs
To address the challenges of analyzing new illicit drugs, emerging techniques, such as ultrahigh performance supercritical fluid chromatography (UHPSFC) with mass spectrometry (MS) and ultraviolet (UV) detection, and gas chromatography (GC) with vacuum ultraviolet (VUV) detection, may be needed, particularly for distinguishing positional isomers and diastereomers.
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